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Elsa G Guillot

Computational Biostatistics

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Following an engineering degree in modeling biological systems, a master degree in modeling complex systems and a PhD in statistics, my research focuses on modeling human systems (culture, languages, societies, demography) using population genetics datasets.

Current Projects

Modelling social processes and population gentics

Correcting gene length biases in bioinformatics

With Jerome Goudet (UNIL) and Marc Robinson-Réchavi (UNIL)

Publications

Wheway, G., A. Douglas, D. Baralle, and E. Guillot (2020). Mutation spectrum of PRPF31, genotype-phenotype correlation in retinitis pigmentosa, and opportunities for therapy. Experimental Eye Research, p.107950. doi:https://doi.org/10.1016/j.exer.2020.107950

Lansing, J.S., C. Abundo, G.S. Jacobs, E.G. Guillot, S. Thurner, S.S. Downey, L.Y. Chew, T. Bhattacharya, H. Sudoyo and M.P. Cox (2017) Kinship Structures Create Persistent Channels for Language Transmission. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.1706416114

Kanitz R., E.G. Guillot, S. Antoniazza, S. Neuenschwander and J. Goudet.2018. Complex genetic patterns in human arise from a simple range-expansion model over continental landmasses. PLoS One 13(2). doi:10.1371/journal.pone.0192460

Motsch S., M. Moussaid, E.G. Guillot, M. Moreau, J. Pettre, G. Theraulaz, C. Appert-Rolland and P. Degond. Forecasting crowd dynamics through coarse-grained data analysis. Biorxiv 2017. doi:10.1101/175760

Guillot E.G. Modeling the role of social structures in population genetics. PhD Thesis at Massey university pdf here

Guillot E.G. and M.P. Cox High Frequency Haplotypes are Expected Events, not Historical Figures [version 2; referees: 1 approved, 2 approved with reservations] F1000Research 2015, 4:666 doi:10.12688/f1000research.7023.2

Guillot, E.G., M.L. Hazelton, T.M. Karafet, J.S. Lansing, H. Sudoyo and M.P. Cox (2015) Relaxed Observance of Traditional Marriage Rules Allows Social Connectivity without Loss of Genetic Diversity. Molecular Biology and Evolution 32:2254-2262 doi: 10.1093/molbev/msv102

Guillot, E.G. and M.P. Cox (2014) SMARTPOP: Inferring the Impact of Social Dynamics on Genetic Diversity through High Speed Simulations. BMC Bioinformatics 15:175 doi 10.1186/1471210515175

Guillot, E.G., M.K. Tumonggor, J.S. Lansing, H. Sudoyo and M.P. Cox (2013) Climate Change Influenced Female Population Sizes through Time across the Indonesian Archipelago. Human Biology 85:135152 doi : 10.3378/027.085.0306

Moussaïd, M., E.G. Guillot, M. Moreau, J. Fehrenbach, O. Chabiron, S. Lemercier, J. Pettré, C. AppertRolland, P. Degond and G. Theraulaz (2012) Traffic Instabilities in Self-Organized Pedestrian Crowds. PLoS Computational Biology 8, 3: e100244 doi : 10.1371/journal.pcbi.1002442

CV

Since 2018 - Lecturer in statistics

Department of Engineering, Design and Mathematics, University of the West of England, Bristol, UK

2015-2017 Post-Doctorat

Département Écologie et Évolution, Université de Lausanne, Suisse

With Prof. Marc Robinson-Réchavi and Prof. Jérôme Goudet

2011-2015 PhD in statistics

“Modeling the role of social structures in population genetics” Institute of fundamental Sciences (IFS), Massey University, Palmerston North, New-Zealand (NZ)

Distinction : Dean’s list of exceptionnal thesis

Supervised by Prof. Murray P Cox and Prof. Martin L Hazelton

2010-2011 Master, computer sciences option modeling of complex systems

IXXI, École Normale Supérieure (ENS), Lyon, France

2006-2011 Master of Engineering, speciality in bioinformatics and modeling

BIM, Institut National des Sciences Appliquées (INSA), Lyon, France

2011 Master project

“Modeling bidirectional flow of pedestrians”

CRCA, University Paul Sabatier, Toulouse, France

With Prof. Guy Theraulaz

Software

SMARTPOP

Forward-in-Time simulations of structured population genetics

http://smartpop.sourceforge.net

CARPnTREES

Reconstructing female and male lineages from haplogroups in humans (with Marie Zufferey)

http://carpntrees.shinyapps.io/shinyapp

Research Interests

Computational statistics:

Biostatistics:

Teaching experience and interest

Others

My Erdős number is 4

Member of the International Society of Computation Biology Regional Student Group of Switzerland

Outreach Participation in a Science video hackathon

http://www.unil.ch/dee/en/home/menuinst/people/post-docs–associates/dr-elsa-guillot.html

Twitter: @elza_guillot

UWE webpage

Contact: elsa.guillot@unil.ch