Elsa G Guillot

Computational Biostatistics

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Following an engineering degree in modeling biological systems, a master degree in modeling complex systems and a PhD in statistics, my research focuses on modeling human and biological systems: culture, languages, societies, demography, genetics.

After 8 years in Academia I joined Vidium Solution in 2020 as a system biologist to model cell fate from OMICS data, before progressing to CTO and COO.

Short CV

For a more detailed version sse my cv or my linkedin profile

2020 - 2024 - System Biologist

COO since 2022 CTO since 2023

Vidium Solutions, Lyon, France

2018-2020 - Lecturer in Statistics

Department of Engineering, Design and Mathematics, University of the West of England, Bristol, UK

2015-2017 Post-Doc

Département Écologie et Évolution, Université de Lausanne, Suisse

With Prof. Marc Robinson-Réchavi and Prof. Jérôme Goudet

2011-2015 PhD in (bio)statistics

“Modeling the role of social structures in population genetics” Institute of fundamental Sciences (IFS), Massey University, Palmerston North, New-Zealand (NZ)

Distinction : Dean’s list of exceptionnal thesis

Supervised by Prof. Murray P Cox and Prof. Martin L Hazelton

2010-2011 Master of Sciences, computer sciences and modeling of complex systems

IXXI, École Normale Supérieure (ENS), Lyon, France

2006-2011 Master of Engineering, specialized in bioinformatics and modeling

BIM, Institut National des Sciences Appliquées (INSA), Lyon, France

2011 Master project

“Modeling bidirectional flow of pedestrians”

CRCA, University Paul Sabatier, Toulouse, France

With Prof. Guy Theraulaz

Publications

Gwynllyw, D. R., Henderson, K. L., & Guillot, E. G. (2020). Using Python in the Teaching of Numerical Analysis. MSOR Connections, 18(2).

Wheway, G., A. Douglas, D. Baralle, and E. Guillot (2020). Mutation spectrum of PRPF31, genotype-phenotype correlation in retinitis pigmentosa, and opportunities for therapy. Experimental Eye Research, p.107950. doi:https://doi.org/10.1016/j.exer.2020.107950

Kanitz R., E.G. Guillot, S. Antoniazza, S. Neuenschwander and J. Goudet.2018. Complex genetic patterns in human arise from a simple range-expansion model over continental landmasses. PLoS One 13(2). doi:10.1371/journal.pone.0192460

Motsch S., M. Moussaid, E.G. Guillot, M. Moreau, J. Pettre, G. Theraulaz, C. Appert-Rolland and P. Degond. (2018) Forecasting crowd dynamics through coarse-grained data analysis. Mathematical Biosciences & Engineering doi: 10.3934/mbe.2018059

Lansing, J.S., C. Abundo, G.S. Jacobs, E.G. Guillot, S. Thurner, S.S. Downey, L.Y. Chew, T. Bhattacharya, H. Sudoyo and M.P. Cox (2017) Kinship Structures Create Persistent Channels for Language Transmission. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.1706416114

Guillot E.G. Modeling the role of social structures in population genetics. PhD Thesis at Massey university pdf here

Guillot E.G. and M.P. Cox High Frequency Haplotypes are Expected Events, not Historical Figures [version 2; referees: 1 approved, 2 approved with reservations] F1000Research 2015, 4:666 doi:10.12688/f1000research.7023.2

Guillot, E.G., M.L. Hazelton, T.M. Karafet, J.S. Lansing, H. Sudoyo and M.P. Cox (2015) Relaxed Observance of Traditional Marriage Rules Allows Social Connectivity without Loss of Genetic Diversity. Molecular Biology and Evolution 32:2254-2262 doi: 10.1093/molbev/msv102

Guillot, E.G. and M.P. Cox (2014) SMARTPOP: Inferring the Impact of Social Dynamics on Genetic Diversity through High Speed Simulations. BMC Bioinformatics 15:175 doi 10.1186/1471210515175

Guillot, E.G., M.K. Tumonggor, J.S. Lansing, H. Sudoyo and M.P. Cox (2013) Climate Change Influenced Female Population Sizes through Time across the Indonesian Archipelago. Human Biology 85:135152 doi : 10.3378/027.085.0306

Moussaïd, M., E.G. Guillot, M. Moreau, J. Fehrenbach, O. Chabiron, S. Lemercier, J. Pettré, C. AppertRolland, P. Degond and G. Theraulaz (2012) Traffic Instabilities in Self-Organized Pedestrian Crowds. PLoS Computational Biology 8, 3: e100244 doi : 10.1371/journal.pcbi.1002442

Software

SMARTPOP

Forward-in-Time simulations of structured population genetics

http://smartpop.sourceforge.net

CARPnTREES

Reconstructing female and male lineages from haplogroups in humans (with Marie Zufferey)

http://carpntrees.shinyapps.io/shinyapp

Languages

R, python, C++, SQL, bash, latex

Research Interests

Computational statistics:

Biostatistics:

Teaching experience

I have taught at university level (bachelor and masters) in France, Switzerland, New Zealand and England, spanning a wide variety of topics:

Interest

Others

My Erdős number is 4

Member of the French Society of Bioinformatics

Former number of :

Outreach: Participation in a Science video hackathon

Linkedin: https://www.linkedin.com/in/elsaguillot/

Contact: elza [dot] guillot at gmail [dot] com