Following an engineering degree in modeling biological systems, a master degree in modeling complex systems and a PhD in statistics, my research focuses on modeling human and biological systems: culture, languages, societies, demography, genetics.
After 8 years in Academia I joined Vidium Solution in 2020 as a system biologist to model cell fate from OMICS data, before progressing to CTO and COO.
Short CV
For a more detailed version sse my cv or my linkedin profile
2020 - 2024 - System Biologist
COO since 2022 CTO since 2023
Vidium Solutions, Lyon, France
2018-2020 - Lecturer in Statistics
Department of Engineering, Design and Mathematics, University of the West of England, Bristol, UK
2015-2017 Post-Doc
Département Écologie et Évolution, Université de Lausanne, Suisse
With Prof. Marc Robinson-Réchavi and Prof. Jérôme Goudet
2011-2015 PhD in (bio)statistics
“Modeling the role of social structures in population genetics” Institute of fundamental Sciences (IFS), Massey University, Palmerston North, New-Zealand (NZ)
Distinction : Dean’s list of exceptionnal thesis
Supervised by Prof. Murray P Cox and Prof. Martin L Hazelton
2010-2011 Master of Sciences, computer sciences and modeling of complex systems
IXXI, École Normale Supérieure (ENS), Lyon, France
2006-2011 Master of Engineering, specialized in bioinformatics and modeling
BIM, Institut National des Sciences Appliquées (INSA), Lyon, France
2011 Master project
“Modeling bidirectional flow of pedestrians”
CRCA, University Paul Sabatier, Toulouse, France
With Prof. Guy Theraulaz
Publications
Gwynllyw, D. R., Henderson, K. L., & Guillot, E. G. (2020). Using Python in the Teaching of Numerical Analysis. MSOR Connections, 18(2).
Wheway, G., A. Douglas, D. Baralle, and E. Guillot (2020). Mutation spectrum of PRPF31, genotype-phenotype correlation in retinitis pigmentosa, and opportunities for therapy. Experimental Eye Research, p.107950. doi:https://doi.org/10.1016/j.exer.2020.107950
Kanitz R., E.G. Guillot, S. Antoniazza, S. Neuenschwander and J. Goudet.2018. Complex genetic patterns in human arise from a simple range-expansion model over continental landmasses. PLoS One 13(2). doi:10.1371/journal.pone.0192460
Motsch S., M. Moussaid, E.G. Guillot, M. Moreau, J. Pettre, G. Theraulaz, C. Appert-Rolland and P. Degond. (2018) Forecasting crowd dynamics through coarse-grained data analysis. Mathematical Biosciences & Engineering doi: 10.3934/mbe.2018059
Lansing, J.S., C. Abundo, G.S. Jacobs, E.G. Guillot, S. Thurner, S.S. Downey, L.Y. Chew, T. Bhattacharya, H. Sudoyo and M.P. Cox (2017) Kinship Structures Create Persistent Channels for Language Transmission. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.1706416114
Guillot E.G. Modeling the role of social structures in population genetics. PhD Thesis at Massey university pdf here
Guillot E.G. and M.P. Cox High Frequency Haplotypes are Expected Events, not Historical Figures [version 2; referees: 1 approved, 2 approved with reservations] F1000Research 2015, 4:666 doi:10.12688/f1000research.7023.2
Guillot, E.G., M.L. Hazelton, T.M. Karafet, J.S. Lansing, H. Sudoyo and M.P. Cox (2015) Relaxed Observance of Traditional Marriage Rules Allows Social Connectivity without Loss of Genetic Diversity. Molecular Biology and Evolution 32:2254-2262 doi: 10.1093/molbev/msv102
Guillot, E.G. and M.P. Cox (2014) SMARTPOP: Inferring the Impact of Social Dynamics on Genetic Diversity through High Speed Simulations. BMC Bioinformatics 15:175 doi 10.1186/1471210515175
Guillot, E.G., M.K. Tumonggor, J.S. Lansing, H. Sudoyo and M.P. Cox (2013) Climate Change Influenced Female Population Sizes through Time across the Indonesian Archipelago. Human Biology 85:135152 doi : 10.3378/027.085.0306
Moussaïd, M., E.G. Guillot, M. Moreau, J. Fehrenbach, O. Chabiron, S. Lemercier, J. Pettré, C. AppertRolland, P. Degond and G. Theraulaz (2012) Traffic Instabilities in Self-Organized Pedestrian Crowds. PLoS Computational Biology 8, 3: e100244 doi : 10.1371/journal.pcbi.1002442
Software
SMARTPOP
Forward-in-Time simulations of structured population genetics
http://smartpop.sourceforge.net
CARPnTREES
Reconstructing female and male lineages from haplogroups in humans (with Marie Zufferey)
http://carpntrees.shinyapps.io/shinyapp
Languages
R, python, C++, SQL, bash, latex
Research Interests
Computational statistics:
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Inference tools using heavy programming machinery
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Simulation models
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Bayesian inferences
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Big data
Biostatistics:
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Population genetics
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Social evolution (culture, languages, marriage rules)
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Genetic evolution
Teaching experience
I have taught at university level (bachelor and masters) in France, Switzerland, New Zealand and England, spanning a wide variety of topics:
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Data science
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Multivariate statistics
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Statistical analyses
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Statistical research methods
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Numerical methods
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Mathematics for engineers
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Statistics for non specialists (biology, business, sports)
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Population genetics
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Modeling and simulations
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Programming (R, python)
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Modeling
Interest
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Complexity
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Modeling
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Statistics
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Bioinformatics
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OMICS
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Data science
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IA
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Mentoring
Others
My Erdős number is 4
Member of the French Society of Bioinformatics
Former number of :
Outreach: Participation in a Science video hackathon
Linkedin: https://www.linkedin.com/in/elsaguillot/
Contact: elza [dot] guillot at gmail [dot] com